(HealthDay)—The U.S. Food and Drug Administration has announced the approval of Dovato (dolutegravir and lamivudine), the first approved two-drug, fixed-dose, complete regimen for adults with HIV-1 who have not been previously treated with antiretroviral medication. Dovato is indicated for patients with no known or suspected substitutions associated with resistance to the drug’s individual components. As opposed to the standard-of-care three-drug regimen, Dovato provides patients with the option of...
Tag: <span>HIV</span>
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Immunotherapy kicks and kills HIV by exploiting a common virus
by University of Pittsburgh In a first on the quest to cure HIV, University of Pittsburgh Graduate School of Public Health scientists report today in EBioMedicine that they’ve developed an all-in-one immunotherapy approach that not only kicks HIV out of hiding in the immune system, but also kills it. The key lies in immune cells designed to recognize an entirely different virus. The discovery, made...
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Researchers uncover new facets of HIV’s ‘arms race’ with human defense system
A new study reveals details about the evolutionary contest between HIV and the human immune system that could one day improve treatment. Research led by Shan-Lu Liu of The Ohio State University demonstrates the important role of one protein in allowing HIV to flourish within human cells despite the immune system’s efforts to beat it...
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Using anti-cancer immunotherapy to fight HIV
Researchers at the University of Montreal Hospital Research Centre (CRCHUM) have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. In a study published in the journal Nature Communications, they show, in the cells of people living with HIV, how these therapies reveal the virus—until...
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Is a cure for Aids within reach? Scientists succeed in destroying HIV-infected cells in major breakthrough
Scientists announced a potential breakthrough in the fight against HIV/AIDS Researchers at Paris’ Institut Pasteur found a way to destroy infected cells Currently HIV is treated with antiretroviral drugs which cannot remove the virus Researchers claim to have found a way to eliminate infected ‘reservoir’ cells Scientists have announced a potentially major breakthrough in the...
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Why you cannot get HIV from kissing
A person can transmit HIV through blood, semen, and breast milk. However, HIV cannot survive in saliva, so there is no risk of contracting HIV through kissing. HIV is a virus that weakens the immune system, which can leave the body vulnerable to infections and diseases. A person can transmit HIV through certain bodily fluids, such...
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Sensitive tests suggest low risk of drug resistance with dapivirine ring
New results presented at HIVR4P finds no dapivirine-associated resistance detected among women who acquired HIV while using dapivirine vaginal ring in ASPIRE MICROBICIDE TRIALS NETWORK MADRID, October 24, 2018 – A monthly vaginal ring that slowly releases an antiretroviral (ARV) drug called dapivirine is currently undergoing regulatory review. If approved, the dapivirine ring would be the first biomedical HIV prevention method developed...
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Scientists develop rapid test for diagnosing tuberculosis in people with HIV
An international team that includes Rutgers scientists has made significant progress in developing a urine diagnostic test that can quickly, easily and inexpensively identify tuberculosis infection in people also infected with HIV. TB is the leading infectious disease killer in the world and the most common cause of death for people living with HIV, although...
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HIV treatment-as-prevention is effective in homosexual male couples, study finds
July 17, 2018 by Estelle Jones, University of New South Wales A study led by the Kirby Institute at UNSW supports evidence that treatment-as-prevention allows people living with HIV to have effectively zero chance of sexually transmitting the virus to others. Results from a large study of HIV transmission risk among homosexual male couples with differing...
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Candidate AIDS vaccine passes key early test
Paris (AFP) – The near 40-year quest for an AIDS vaccine received a hopeful boost Saturday when scientists announced that a trial drug triggered an immune response in humans and shielded monkeys from infection. Scientists announced that a trial drug against the AIDS vaccine has yielded encouraging results and has advanced to the next phase...