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People with HIV are at higher risk of ageing-related genetic changes
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People with HIV are at higher risk of ageing-related genetic changes

by  University of New South Wales The question of how HIV affects the aging process is becoming an increasingly important field of research. Credit: Shutterstock We don’t know enough about biological processes in people who are aging with HIV—a new study sheds light on the matter. Forty years after the first diagnosis of HIV/AIDS, Australian scientists...

Noncalcified coronary plaque burden higher in people with HIV
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Noncalcified coronary plaque burden higher in people with HIV

RADIOLOGICAL SOCIETY OF NORTH AMERICA IMAGE: Noncalcified coronary plaque in an asymptomatic 52-year-old man living with HIV with a 10-year Framingham risk of 5%. Images show 256-section contrast-enhanced coronary CT angiography with electrocardiographic gating and curve reformat. A, B, CT scan shows a smooth noncalcified plaque in the right coronary artery (arrows) with 70%-80% stenosis....

Fungal disease diagnosis is life saver for patients with HIV and AIDS
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Fungal disease diagnosis is life saver for patients with HIV and AIDS

A fungal disease diagnostic and educational programme has had a transformational impact on the mortality of HIV patients in Guatemala, according to new research. And the programme, say scientists at the Asociación de Salud Integral (ASI) in Guatemala City and The University of Manchester, will save lives in countries across the developing world if implemented. Image credit: University...

Study finds low awareness of PrEP, the highly effective medication that protects individuals from HIV
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Study finds low awareness of PrEP, the highly effective medication that protects individuals from HIV

by  Johns Hopkins University Bloomberg School of Public Health Pre-Exposure Prophylaxis (PrEP)- Single pills (brand name Truvada) containing two antiretroviral drugs, emtricitabine and tenofovir disoproxyl fumarate. Truvada is used for pre-exposure prophylaxis, or PrEP, a strategy in which healthy people routinely take antiretrovirals to reduce the risk of becoming infected with HIV. Credit: NIAID A study...

HIV: an innovative therapeutic breakthrough to optimize the immune system
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HIV: an innovative therapeutic breakthrough to optimize the immune system

INSTITUT NATIONAL DE LA RECHERCHE SCIENTIFIQUE – INRS IMAGE: INRS PROFESSOR JULIEN VAN GREVENYNGHE, EXPERT IN IMMUNOLOGY AND VIROLOGY, AND DOCTORAL STUDENT HAMZA LOUCIF, FIRST AUTHOR OF THE PAPER. CREDIT: INRS Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la...

Human immune cells have natural alarm system against HIV
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Human immune cells have natural alarm system against HIV

by  Washington University School of Medicine HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia Treatment for HIV has improved tremendously over the past 30 years; once a death sentence, the disease is now a manageable lifelong condition in many parts of the world. Life expectancy is about the same as that of individuals without HIV, though patients must...

‘Repliclones’ fuel perplexing persistence of HIV in the blood of some patients on therapy
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‘Repliclones’ fuel perplexing persistence of HIV in the blood of some patients on therapy

by  University of Pittsburgh Endowed Chair for Global Elimination of HIV and AIDS, and chief of the Division of Infectious Diseases at Pitt and UPMC. Increasingly, UPMC’s chief of infectious diseases—a well-regarded expert in HIV/AIDS—is contacted by a perplexed physician describing a patient with HIV who insists they are adhering to the daily medication regimen meant...

COVID-19 and mRNA Vaccines—First Large Test for a New Approach
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COVID-19 and mRNA Vaccines—First Large Test for a New Approach

On January 10, Chinese researchers posted the novel coronavirus’ RNA sequence on a preprint server. Immediately, scientists who study genetic vaccines turned their efforts to the emerging pathogen that causes coronavirus disease 2019 (COVID-19). They knew that rapid response genetic platforms could shave precious weeks to months off development, crucial during a pandemic. They were...

COVID-19 and mRNA Vaccines—First Large Test for a New Approach
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COVID-19 and mRNA Vaccines—First Large Test for a New Approach

n January 10, Chinese researchers posted the novel coronavirus’ RNA sequence on a preprint server. Immediately, scientists who study genetic vaccines turned their efforts to the emerging pathogen that causes coronavirus disease 2019 (COVID-19). They knew that rapid response genetic platforms could shave precious weeks to months off development, crucial during a pandemic.\ They were...

Scientists discover that a normal DNA repair process can become a major source of mutations in cancer
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Scientists discover that a normal DNA repair process can become a major source of mutations in cancer

by Institute for Research in Biomedicine – IRB Hypermutation is an unusual occurence that can lead to many nearby mutations at once, severely damaging our genetic material and potentially causing cancer. The best known type of local hypermutation, called a mutation shower or thunderstorm, is quite uncommon and it leads to many mutations accumulated in...