by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, published in Cell Reports Medicine, aims to create a functional HIV cure by activating and then eliminating all pockets of...
by Yale University Yale researchers have identified four drugs that may help minimize the long-term health effects of HIV infection, they report June 23 in the Journal of Clinical Investigation. Antiretroviral therapy has proved to be a life-saving treatment for those infected with HIV. Yet even after treatment, most patients still harbor latent HIV in...
By Linda NordlingJun. 15, 2020 , 4:30 PM Science’s COVID-19 reporting is supported by the Pulitzer Center. CAPE TOWN, SOUTH AFRICA—Living with HIV or active tuberculosis (TB) increases a person’s likelihood of dying from COVID-19, preliminary data from South Africa show. However, the effect is small compared with other known risk factors such as old...
As it stands, there are two drugs that have been approved by the Food and Drug Administration to be prescribed as PrEP, an HIV prevention strategy that when taken routinely makes it virtually impossible to contract the virus. Both of these daily drugs, Truvada and Descovy, are manufactured by Gilead. In the last couple years,...
Sandra Adamson Fryhofer, MD, MACP, FRCP DISCLOSURES February 12, 2020 This transcript has been edited for clarity. Hello. I’m Dr Sandra Fryhofer. Welcome to Medicine Matters. The topic? HPV vaccine for mid-life adults. Who needs it? Who doesn’t? A new study was published in JAMA Network. HPV, the human papilloma virus, causes cancer—as many as...
In a new study, an alternative treatment regimen that is less toxic than standard dose-intensive chemotherapy was found to be highly effective for adults with Burkitt lymphoma across all age groups and independent of HIV status. In addition to being better tolerated, the regimen, called dose-adjusted (DA) EPOCH-R, is already an option for diffuse large...
by University of North Carolina at Chapel Hill School of Medicine The HIV Prevention Trials Network (HPTN) announced today results from HPTN 083, a global randomized, controlled, double-blind study that compared the safety and efficacy of long-acting injectable cabotegravir (CAB LA) to daily oral tenofovir/emtricitabine (TDF/FTC) (Truvada) for pre-exposure prophylaxis (PrEP). The study showed that...
By SASHA CUTTLER, MARY MAGEE, and GUY VANDENBERGMAY 18, 2020 As nurses who worked in 5B, the first U.S. hospital ward dedicated HIV/AIDS, which opened in San Francisco General Hospital in 1983, we have been directly affected in profound ways by the disease and its opportunistic infections. One of us is HIV-positive, infected from exposure...
Some people with HIV need to undergo an allogeneic stem cell transplantation in order to treat different types of blood cancer. Most of the patient’s immune cells are eliminated during these transplantations. Stem cells from a healthy donor are then used to replace the patient’s damaged bone marrow and restore their immune system. “In the...
A nasal spray derived from algae and a plant in the tobacco family could offer a preventive measure for COVID-19, according to a new study. Researchers are making a molecule called Q-griffithsin using an anti-viral protein found in the New Zealand red algae Griffithsia and Nicotiana benthamiana, a plant in the same family as tobacco...
