by The Feinstein Institutes for Medical Research HMGB1 is actively released by stimulated sensory neurons. (A and B) Optogenetic stimulation of sensory neurons induces HMGB1 release. DRG neurons harvested from VGlut2-ChR2-YFP mice were stimulated with control yellow light (595 nm, n = 3) or blue light (470 nm, n = 4) at 20 Hz, 10% duty cycle...
