Tag: <span>HMGB1</span>

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HMGB1 released from nociceptors mediates inflammation
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HMGB1 released from nociceptors mediates inflammation

by  The Feinstein Institutes for Medical Research HMGB1 is actively released by stimulated sensory neurons. (A and B) Optogenetic stimulation of sensory neurons induces HMGB1 release. DRG neurons harvested from VGlut2-ChR2-YFP mice were stimulated with control yellow light (595 nm, n = 3) or blue light (470 nm, n = 4) at 20 Hz, 10% duty cycle...