by Family Heart Foundation Credit: Unsplash/CC0 Public Domain The Family Heart Foundation, a leading research and advocacy organization, has shared results from an analysis of patients in its CASCADE FH Registry showing that children with homozygous familial hypercholesterolemia (HoFH) are diagnosed earlier and have much higher untreated low-density lipoprotein cholesterol (LDL-C) than adults with HoFH....
This article by Dr. Claudia Stefanutti et al. is published in Current Pharmaceutical Design, Volume 24 , Issue 31 , 2018 BENTHAM SCIENCE PUBLISHERS Research suggests a specific treatment for Homozygous Familial Hypercholesterolaemic (HoFH) patients; combination therapy with PCSK9–inhibitors (PCSK9-I) and lipoprotein–apheresis (LA) may have synergistic effects on circulating lipid and lipoprotein levels. The relationship with the treatment regimen mentioned above...
