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More than just neurons: Scientists create new model for studying human brain inflammation
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More than just neurons: Scientists create new model for studying human brain inflammation

by Salk Institute Human astrocytes (green) extending processes that wrap around the host blood vessel (magenta). Credit: Salk InstituteThe brain is typically depicted as a complex web of neurons sending and receiving messages. But neurons only make up half of the human brain. The other half—roughly 85 billion cells—are non-neuronal cells called glia. The most common...

Deteriorating neurons are source of human brain inflammation in Alzheimer’s disease
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Deteriorating neurons are source of human brain inflammation in Alzheimer’s disease

by Salk Institute Neurons (green) derived from a patient with Alzheimer’s disease. The nuclei (blue) of the neurons are also shown. Credit: Salk Institute Despite decades of research, Alzheimer’s disease remains a debilitating and eventually fatal dementia with no effective treatment options. More than 95 percent of Alzheimer’s disease cases have no known origin. Now,...