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Redefining human diseases through the lens of DNA
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Redefining human diseases through the lens of DNA

by Osaka University Fig.1 Overview of this study. We performed 220 deep-phenotype genome-wide association studies (GWAS) in BioBank Japan, then performed trans-biobank meta-analyses with UK Biobank and FinnGen (ntotal = 628,000). As downstream analyses, we performed (i) cross-population comparisons of pleiotropy and genetic correlations, (ii) comprehensive HLA fine-mapping, and (iii) statistical decomposition of a matrix...