by Walter and Eliza Hall Institute of Medical Research Generation and validation of pdCas9a-SAM construct in Eµ-Myc lymphoma cell lines. a Schematic representation of the pdCas9a-SAM lentiviral construct. b Western blot analysis for BCL-2 in manipulated Eµ-Myc lymphoma cell lines. EMRK-1184 or MRE-721 Eµ-Myc lymphoma-derived cell lines were transduced with pdCas9a-SAM only or pdCas9a-SAM plus Bcl-2...
by Harvard Medical School Credit: Pixabay/CC0 Public Domain We are truly never alone, not even within our own bodies. Human beings play host to trillions of bacteria, fungi, viruses, and other microorganisms that make up the human microbiome. In recent years, the mix of these resident bacteria, and the presence of specific bacterial species, has been...
HIROSHIMA UNIVERSITY IMAGE: (A) BUD STAGE; (B) FLOWERING STAGE; (C) SPIKELETS CREDIT: QUAN, HIROSHIMA UNIVERSITY Native to the southeastern United States, a weedy grass has spread northward to Canada and also made its way to Australia and Japan. Andropogon virginicus grows densely packed and up to seven feet tall, disrupting growth patterns of other plants and competing...
By Dr. Sanchari Sinha Dutta, Ph.D. Endosomes are membrane-bound cytosolic vesicles with three major compartments namely early, late, and recycling endosomal compartments. Endosomes are the integral parts of the endocytic process, and thereby, play crucial roles in various physiological processes, such as nutrient uptake, sorting and delivery of macromolecules, and regulation of cell surface receptors and...
