BY MONIQUE BROUILLETTE PUBLISHED: MAY 6, 2022 Stefania Pelfini, La Waziya Photography//Getty Images Shinya Yamanaka won the Nobel Prize in 2012 for the discovery of his eponymous “Yamanaka factors,” which can revert cells to their embryonic state. The factors seemed promising for reversing signs of aging, but they reset the age of the cells too far back in...
by Lund University HD-iNs exhibit neurite specific autophagy alteration. (A) Reduced BECN1 expression in HD-iNs compared to Ctrl-iNs using western blot (n = 10 replicates for control and n = 9 replicates for HD-iNs). (B) LC3B-II levels are significantly increased in the HD-iNs, while the LC3B-II/I ratio decreased compared to the healthy Ctrl-iNs (n = 6 replicates). (C–H) Representative images and...
