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Primary hyperparathyroidism linked to bone fracture, stroke and heart attack
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Primary hyperparathyroidism linked to bone fracture, stroke and heart attack

by University of Gothenburg Cumulative incidences for patients with primary hyperparathyroidism (pHPT) and control individuals. The cumulative incidence of events for untreated pHPT and control groups was estimated using 1-minus Kaplan-Meier estimate of the corresponding survival function and presented with 95% CIs (indicated by shaded areas). Credit: JAMA Network Open (2022). DOI: 10.1001/jamanetworkopen.2022.15396 In the hormonal disorder...

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Signalling protein discovery may lead to drug-based therapies to treat hyperparathyroidism

DUKE-NUS MEDICAL SCHOOL SINGAPORE, 28 May 2019 – Overactive parathyroid glands,which control the body’s blood calcium levels, can lead to kidney stones, neuropsychiatric disorders and bone abnormalities, particularly among elderly women. Researchers led by Duke-NUS Medical School have discovered a signalling protein that appears to protect these glands from excessive activity, providing insights for drug development to treat hyperparathyroidism – a condition currently treatable only through surgery....