by Anne Doerr, Yale University When antibody-producing immune cells encounter infectious pathogens for the first time, they engage a signal cascade to generate a massive activation signal within seconds. The mechanisms underlying this acute initial activation have not been fully understood. In a new study by Yale Cancer Center, scientists have identified the short endosomal protein...
Tag: <span>Immune cell activation</span>
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Immune cell activation in severe COVID-19 resembles lupus
by Emory University SARS-CoV-2 (shown here in an electron microscopy image). In severe cases of COVID-19, Emory researchers have been observing an exuberant activation of immune cells, resembling acute flares of systemic lupus erythematosus (SLE), an autoimmune disease. Their findings point towards tests that could separate some COVID-19 patients who need immune-calming therapies from others who may not....