IMAGE: NEURAMINIDASE SUPPRESSES AUTOIMMUNE ARTHRITIS AND ENCEPHALOMYELITIS BY INHIBITING DENDRITIC CELL AND OSTEOCLAST ACTIVITY THROUGH REMOVAL OF SIALIC ACID, THEREBY EXPOSING ASIALO-BIANTENNARY N-GLYCAN (NA2) AND GENERATING INHIBITORY SIGNALS THROUGH DENDRITIC CELL IMMUNORECEPTOR (DCIR). CREDIT: YOICHIRO IWAKURA FROM TOKYO UNIVERSITY OF SCIENCE Immune cells play a key role in mediating inflammatory responses. Dysregulation in signaling mechanisms...
by Sarah C. P. Williams, Broad Institute of MIT and Harvard In a subset of human colorectal tumors, immune cells such as activated and potentially tumor-reactive T cells (white, green, and magenta) are organized into “hubs” around malignant cells (blue) expressing molecules (yellow) that attract immune cells. Credit: Joshua Pirl, Vjola Jorgji, Linda Nieman, Jonathan Chen....
by The Mount Sinai Hospital Myeloid immune cells alongside red blood cells in an electron micrograph of human blood. Credit: National Cancer Institute Immune cells that normally repair tissues in the body can be fooled by tumors when cancer starts forming in the lungs and instead help the tumor become invasive, according to a surprising discovery reported...
By Michael Irving May 09, 2021 A microscope image of immune cells (Langerhans cells in red, dendritic epidermal T cells in green) spreading out among the epithelial cells in the skinGreco Lab. The skin is the body’s first line of defense against potential infection, and new research has brought us closer to understanding how it...
by La Jolla Institute for Immunology Enhancers serve as specific switches that turn on genes in a cell specific manner but it has been difficult to determine which switch is connected to which gene. Credit: Alex Fung The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies...
VIRGINIA COMMONWEALTH UNIVERSITY IMAGE: NEW RESEARCH FINDINGS FROM PAULA BOS, PH.D., IDENTIFIED A TYPE OF IMMUNE CELLS THAT ACTS AS A MAJOR DRIVER OF BREAST CANCER GROWTH BY PREVENTING THE ACCUMULATION OF A SPECIFIC PROTIEN THAT INDUCES ANTI-TUMOR RESPONSES. CREDIT: VCU MASSEY CANCER CENTER Breast cancer is the most common cancer in women worldwide, but...
by Cardiff University Credit: CC0 Public Domain A team of scientists has shown that a key type of immune cell “self-renews” in humans. It is an unexpected discovery, as it was previously thought this specific type of “senescent” killer immune cell had reached “end-stage” and would die following one more stint at helping people fight off—or...
TRINITY COLLEGE DUBLIN Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with “Jekyll and Hyde properties”. These cells play a key protective role in immunity to infection but – if unregulated – also mediate tissue damage in autoimmune disorders. The findings should help us design more effective vaccines...
Posted Today Every tissue in the human body has an immune cell in it called a macrophage. Macrophages play important roles in the immune system’s initial response to bacteria, viruses and wounds. But beyond that, each tissue macrophage also has specialized functions, tuned to the needs of that particular tissue. For example, macrophages in the brain, called microglia, help support normal brain development....
Scientists at the University of Dundee have carried out one of the most comprehensive studies into how immune cells sense and respond to their environment to fight infection and destroy tumours. UNIVERSITY OF DUNDEE Scientists at the University of Dundee have carried out one of the most comprehensive studies into how immune cells sense and...
