by Wellcome Trust Sanger Institute Fig. 1: Properties PU.1 transcription factor QTLs. From: Genetic perturbation of PU.1 binding and chromatin looping at neutrophil enhancers associates with autoimmune disease. Credit: Nature Communications (2021). DOI: 10.1038/s41467-021-22548-8 Researchers have combined genome-wide sequencing and functional profiling of immune cells to understand more about the impact of genetic variants on disease. Certain genetic variants...