Last February, Timothy Ray Brown — a.k.a. ‘the Berlin patient’ — celebrated his 10th birthday. Well, sort of. His ’10th birthday’ actually refers to the 10th anniversary marking his recognition as the only person in the world to be cured of HIV, the virus that causes AIDS. Brown’s incredible story began in 1995 when he was diagnosed...
Tag: <span>Immune cells</span>
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Immune discovery points to therapies to improve stroke recovery
A blood clot forming in the carotid artery. Having a stroke damages immune cells as well as affecting the brain, research has found. The findings help explain why patients have a greater risk of catching life-threatening infections, such as pneumonia, after having a stroke. Therapies that boost survival of the affected immune cells or compensate...
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The Principles of Engineering Immune Cells to Treat Cancer
Chimeric antigen receptor (CAR) T cells have proven that engineered immune cells can serve as a powerful new class of cancer therapeutics. Clinical experience has helped to define the major challenges that must be met to make engineered T cells a reliable, safe, and effective platform that can be deployed against a broad range of tumors. The...
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Tracking movement of immune cells identifies key first steps in inflammatory arthritis
Identification of molecule required for immune cells to enter joint could lead to new treatment approaches In the image on the left, many green-labeled neutrophils carrying the C5a receptor have moved out from the grey blood vessel into the joint of a mouse in which inflammatory arthritis has been induced. In an animal lacking expression...