by Katie Marquedant, Massachusetts General Hospital Credit: CC0 Public Domain Tumor cells typically alter their energy metabolism and increase glucose uptake to support their rapid division and spread. This limits glucose availability for immune cells and therefore dampens the body’s anti-cancer immune response. By searching for proteins that both regulate the metabolism of cancer cells...
Tag: <span>immune evasion</span>
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Shape-shifting stem cells are key to cancer metastasis and immune evasion
MEMORIAL SLOAN KETTERING CANCER CENTER Just as people tend to become stuck in their ways as they grow older so too do cells. Neurons in the brain don’t one day decide to become heart cells; skin cells repair wounds with skin cells rather than kidney cells. Cancer cells, on the other hand, are like perpetual...
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Blood-clotting protein and blood platelets promote immune evasion, cancer progression
by Ohio State University Medical Center A new study led by researchers at The Ohio State University Comprehensive Cancer Center—Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC—James) reveals how a clotting protein and blood platelets can promote cancer progression and suppress immune responses to cancer. The findings show how thrombin, a...