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A neural mechanism that could underlie fasting-mediated immune regulation
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A neural mechanism that could underlie fasting-mediated immune regulation

by Ingrid Fadelli , Medical Xpress Model of neuronal regulation of the immune system during fasting. Orexigenic CAVLM neurons are activated during fasting, whose activation stimulates the release of glucocorticoids via the CAVLM→CRHPVN neural circuit targeting the adrenal glands, thereby driving T-cell homing to the bone marrow in a CXCR4CXCL12 axis-dependent manner and suppressing autoimmune...