Gwendolyn Rak Neurologic damage following acute viral infections may be attributed to an excessive immune response to the infection, according to a new study.Many viral infections that don’t directly infect the central nervous system (CNS) have been associated with severe neurologic disease. For these viruses, including newer viruses such as SARS-CoV-2 and Zika, the mechanism...
Tag: <span>immune response</span>
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Immune response, not acute viral infections, responsible for neurological damage, researchers discover
by McMaster University Credit: Pixabay/CC0 Public DomainFor years, there has been a long-held belief that acute viral infections like Zika or COVID-19 are directly responsible for neurological damage, but researchers from McMaster University have now discovered that it’s the immune system’s response that is behind it. The research, published on Feb. 5, 2024, in Nature Communications,...
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New ‘dictionary’ of immune responses reveals far more complexity in the immune system than previously thought
by Allessandra DiCorato, Broad Institute of MIT and Harvard Cytokine production map by cell type. Credit: Nature (2023). DOI: 10.1038/s41586-023-06816-9 The immune system can carry out many biological processes, from killing viruses to fighting cancer, thanks in large part to approximately 100 key cell-signaling proteins called cytokines, which instruct immune cells what to do. Cytokines are...
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Immune health—an immunologist explains why both too strong and too weak an immune response can lead to illness
by Aimee Pugh Bernard, The Conversation Too much or too little immune activation can lead to illness. Credit: Kevbonham/Wikimedia Commons, CC BY-SA For immune health, some influencers seem to think the Goldilocks philosophy of “just right” is overrated. Why settle for less immunity when you can have more? Many social media posts push supplements and...
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Unveiling a novel immune response in the intestinal epithelium
by Charles University Immune response to SFB bacteria in the intestines. Credit: Katarína Kováčová Researchers from the Jan Dobeš laboratory at Charles University in Prague have made a significant discovery uncovering a novel immune response in the intestinal epithelium. Furthermore, their study delineates a mechanism that controls this immune response. Their findings were recently published in...
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Newly discovered compound blocks signaling pathway of immune response
by CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences SLC15A4-TASL binding interface and drug screening for TASL stability. Credit: Nature Communications (2023). DOI: 10.1038/s41467-023-42070-3Scientists at CeMM, the Medical University of Vienna, and the University of Lausanne have succeeded for the first time in identifying and characterizing a new small molecule called...