by University of Bristol Credit: Pixabay/CC0 Public Domain A link between depression and changes in counts of several types of immune cells in the blood has been revealed by researchers at the University of Bristol’s MRC Integrative Epidemiology Unit. These findings, published in Molecular Psychiatry, suggest that changes to different components of our immune system—both the innate and...
by Mark Derewicz, University of North Carolina School of Medicine Viruses (EBV and KSHV) surrounding cells. Credit: Damania Lab The viruses Kaposi sarcoma-associated herpesvirus (KSHV) and Epstein-Barr virus (EBV) have been linked to several cancers. For the first time, UNC School of Medicine scientists have discovered that these viruses use a human protein called barrier-to-autointegration...
by Erik Robinson, Oregon Health & Science University Longitudinal cohort of previously infected vaccinees shows improved variant neutralization compared to vaccination aloneRepresentative focus reduction neutralization test (FRNT) results showing wells infected with live SARS-CoV-2 with the addition of serially diluted serum which were stained and counted (A). Representative focus reduction neutralization curve showing the average...
by King’s College London Credit: CC0 Public Domain When we consume fats (also called lipids) in our diet, they can be metabolized or stored to provide energy for the body. But they are also involved in regulating the genes expressed within—and the signaling between—cells. Lipids influence how our cells behave and function, which affects many...
by Lauran Neergaard Credit: Pixabay/CC0 Public Domain Pfizer said Friday that its updated COVID-19 booster may offer some protection against newly emerging omicron mutants even though it’s not an exact match. Americans have been reluctant to get the updated boosters rolled out by Pfizer and rival Moderna, doses tweaked to target the BA.5 omicron strain...
by Ingrid Fadelli, Medical Xpress To characterize aging effect at single cell resolution, Kaya et al. used two different single-cell RNA sequencing (scRNA-seq) methods. For plate-based scRNA-seq (Smart-seq2). They isolated and dissociated grey matter from the frontal cortex and white matter tracts from the corpus callosum as well as the optical tracts and the medial...
LUDWIG INSTITUTE FOR CANCER RESEARCH IMAGE: RALPH WEICHSELBAUM, CO-DIRECTOR AT THE LUDWIG CENTER AT CHICAGO CREDIT: LUDWIG CANCER RESEARCH OCTOBER 27, 2022, NEW YORK – A Ludwig Cancer Research study has developed a novel nanotechnology that triggers potent therapeutic anti-tumor immune responses and demonstrated its efficacy in mouse models of multiple cancers. Led by Co-director Ralph Weichselbaum,...
by University of Oklahoma Credit: CC0 Public Domain A research team at the University of Oklahoma published a study in the journal Advanced Science that presents a new approach to triggering an adaptive immune response. The study was led by Handan Acar, Ph.D., the Peggy and Charles Stephenson Assistant Professor of Biomedical Engineering in the Gallogly College of...
by Harish Narasimhan, The Conversation Credit: Pixabay/CC0 Public Domain Viruses that cause respiratory diseases like the flu and COVID-19 can lead to mild to severe symptoms within the first few weeks of infection. These symptoms typically resolve within a few more weeks, sometimes with the help of treatment if severe. However, some people go on...
by University of Oxford Credit: CC0 Public Domain Researchers from the University of Oxford have today reported new findings from a Phase 1 clinical trial studying the immune response and safety of their newly-developed single shot rabies vaccine, ChAdOx2 RabG—with promising results identified. The RAB001 trial was conducted at the University and is the first...
