by Max Delbrück Center for Molecular Medicine Colorized scanning electron micrograph of a T lymphocyte. Credit: NIAID For patients with lymphoma, multiple myeloma, or certain types of leukemia, treatment with chimeric antigen receptor T cells (CAR T cells) is sometimes the last chance of overcoming the cancer. The treatment involves taking T cells from the...
by NIH/National Institute of Allergy and Infectious Diseases Graphical abstract. Credit: Cell Reports Medicine (2022). DOI: 10.1016/j.xcrm.2022.100679 Although COVID-19 booster vaccinations in adults elicit high levels of neutralizing antibodies against the omicron variant of SARS-CoV-2, antibody levels decrease substantially within 3 months, according to new clinical trial data. The findings, published today in Cell Reports Medicine, are from...
by Christina Griffiths, Indiana University School of Medicine An artist’s depiction of a T cell. Credit: NIAID Researchers at Indiana University School of Medicine are learning more about how special regulatory T cells can impact the immune system’s response and how those cells could be manipulated for potential treatments for food allergies and autoimmune diseases. In...
by Cedars-Sinai Medical Center Credit: CC0 Public Domain Cedars-Sinai investigators have identified a gene that plays an essential role in the innate human immune system. The gene, NLRP11, helps activate the inflammatory response that tells the body’s white blood cells to go on the attack against a foreign presence. The findings, published in Nature Immunology, bring...
by American Society for Microbiology Transmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAID By uniting research from eight cohorts across the U.S., a group of researchers has accelerated collection of data integral in answering questions about immune responses needed for long lasting protection from SARS-CoV-2. The description of the cohorts,...
Lei Lei Wu News Reporter Most Alzheimer’s drugs, including Biogen’s aducanumab (Aduhelm) and Eli Lilly’s donanemab, target amyloid plaques, misfolded protein clumps that build up in the brain, which are a hallmark of Alzheimer’s disease. However, researchers from Weill Cornell have uncovered an alternate immune response pathway that could be a potential target for new...
WEST VIRGINIA UNIVERSITY IMAGE: MULTIPLE SCLEROSIS IS A CHRONIC DISEASE THAT DAMAGES NEURONS. A WEST VIRGINIA UNIVERSITY DOCTORAL STUDENT, KELLY MONAGHAN, IS RESEARCHING THE ROLE THAT A PROTEIN, STAT5, PLAYS IN THE DEVELOPMENT OF MS. CREDIT: WVU ILLUSTRATION/AIRA BURKHART A human immune system is a lot like the board game Mouse Trap: it’s a Rube...
by Kiel University Immune responses on intestinal mucosal barriers play a key role in chronic inflammatory bowel diseases. Depicted here is the interaction between T lymphocytes with human leukocyte antigen (HLA) complex and the antigen-presenting cell. Credit: Andre Franke/Renate Nikolaus, Kiel University Chronic inflammatory bowel diseases (IBDs) like Crohn’s disease and ulcerative colitis are characterized...
by University of California – Santa Cruz The engineered RSV G protein, with the RSV G antigen in orange and the human antibody in grey. The arrow points to the place where the researchers engineered the antigen, doing so while not affecting its ability to bind to the antibody. Credit: Rebecca DuBois Close interactions with...
By Rich Haridy February 13, 2022 Around 90 minutes of moderate intensity exercise right after your vaccine dose could improve your immune response Depositphotos New research from Iowa State University has found a long bout of moderately intense exercise following COVID-19 or influenza vaccination can amplify the body’s immune response. The study showed 90 minutes...
