Scientists have produced the first fine-detail molecular blueprints of a bacterial enzyme known as Lit, which is suspected to play a “stealthy” role in the progression of infection by reducing the immune response. Blueprints such as these allow drug designers to uncover potential weaknesses in bacterial arsenals as they seek to develop new therapeutics that may help...
Tag: <span>immune response .</span>
Latest data on immune response to COVID-19 reinforces need for vaccination
by University of Liverpool Credit: University of Liverpool New research has found that previous infection, whether it was symptomatic or asymptomatic, does not necessarily protect you long-term from COVID-19, particularly against new Variants of Concern. The preprint study was led by the University of Oxford, in collaboration with the Universities of Liverpool, Sheffield, Newcastle, and Birmingham...
Direct action of SARS-CoV-2 on organs may cause exacerbated immune response in children
by Elton Alisson, FAPESP Electron micrograph of the brain of a child with MIS-C associated with COVID-19 and encephalopathy: immunohistochemical detection of SARS-CoV-2 nucleocapsid antigen in brain endothelial cells, with cytoplasm stained red. Credit: Amaro Nunes Duarte Neto Besides common symptoms such as fever, cough, and respiratory distress, some children have an atypical form of COVID-19...
Many COVID-19 patients produce immune responses against their body’s tissues or organs
by University of Birmingham Transmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAID A University of Birmingham-led study funded by the UK Coronavirus Immunology Consortium has found that many patients with COVID-19 produce immune responses against their body’s own tissues or organs. COVID-19 has been associated with a variety of unexpected symptoms,...
Mix-and-Match COVID Vaccines Trigger Potent Immune Response
By Ewen Callaway, Nature magazine on May 21, 2021 Countries with fluctuating supplies of COVID-19 vaccines could benefit from using different vaccines for the first and second dose. Credit: Christof Stache Getty Images Vaccinating people with both the Oxford–AstraZeneca and Pfizer–BioNTech COVID-19 vaccines produces a potent immune response against the virus SARS-CoV-2, researchers conducting a study in Spain have found. Preliminary...
New insights into immune response with coronavirus vaccine candidate SolaVAX
by Mary Guiden, Colorado State University The technology being used to create SolaVAX, a coronavirus vaccine candidate, incorporates vitamin B2 or riboflavin, shown here in the lab under black light. Credit: John Eisele/CSU Photography Dr. Izabela Ragan, an assistant professor at Colorado State University, is working in her dream job. A veterinary scientist by training, she...
The secret lives of T cell receptors and their role in the immune response
by Delthia Ricks , Medical Xpress Credit: CC0 Public Domain Canadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components interacts with the cell membrane. The finding sheds new light on the function of T cell receptors, illuminating the role of specific proteins in...
Gut’s immune response in COVID-19 may not provide efficient protection of other organs
FRONTIERS Our guts may not provide long-lasting systemic immunity from COVID-19, which is where immune cells circulate through the body to provide protection to other organs, finds a new study published in Frontiers in Immunology. An analysis of blood samples from patients infected with SARS-CoV-2 revealed that immune cells circulating in the blood, which were triggered...
New understanding of the deleterious immune response in rheumatoid arthritis
by Monash University Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes associated with the development of rheumatoid arthritis (RA). Credit: Erica Tandori Researchers within the Biomedicine Discovery Institute at Monash University have made a breakthrough in understanding the role played by high-risk immune genes...
Trial shows York leishmaniasis vaccine safe and induces immune responses in patients
UNIVERSITY OF YORK The results of the first clinical trial of a new vaccine for a neglected tropical disease have demonstrated that it is safe and induces immune responses in patients with the infection. There are currently no vaccines to prevent leishmaniasis which is spread by the bite of sand flies and existing drugs have...