SHINSHU UNIVERSITY IMAGE: THE INHIBITION OF IFN-Γ PRODUCTION IN CD4+ T CELLS CAUSED BY THE DIETARY POLYPHENOL PCB2DG WAS MEDIATED BY THE ACTIVATION OF THE AAR PATHWAY THROUGH INHIBITION OF GLUTAMINE INFLUX VIA THE DIRECT INTERACTION OF PCB2DG WITH ASCT2. CREDIT: KATSUNORI ENDO AND SACHI TANAKA, SHINSHU UNIVERSITY PCB2DG, a polyphenol with anti-inflammatory properties, works...
by Weill Cornell Medical College Color-enhanced goblet cells (dark purple) in lung epithelium. Credit: Dr. Mohammad Arifuzzaman and Dr. David Artis A type of dietary fiber called inulin, commonly used in health supplements and known to have certain anti-inflammatory properties, can also promote an allergy-related type of inflammation in the lung and gut, and other...
by Weill Cornell Medical College Confocal microscopy image shows that DNA (green) and the chemokine CXCL4 (red) colocalize (indicated by yellow areas) during inflammatory responses in the skin. Credit: Barrat lab Small proteins, called chemokines, that direct immune cells toward sites of infection can also form DNA-bound nanoparticles that can induce chronic, dysfunctional immune responses, according...
INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO IMAGE: RESEARCHERS FROM THE UNIVERSITY OF TOKYO INSTITUTE OF INDUSTRIAL SCIENCE DESCRIBE A NOVEL FEATURE OF THE IMMUNE RESPONSE TO CERTAIN VIRUSES SUCH AS MEASLES CREDIT: INSTITUTE OF INDUSTRIAL SCIENCE, THE UNIVERSITY OF TOKYO Tokyo, Japan – Researchers from The University of Tokyo Institute of Industrial Science...
ST. JUDE CHILDREN’S RESEARCH HOSPITAL IMAGE: CORRESPONDING AUTHOR THIRUMALA-DEVI KANNEGANTI, PH.D., IS THE VICE-CHAIR OF THE IMMUNOLOGY DEPARTMENT AT ST. JUDE CHILDREN’S RESEARCH HOSPITAL. CREDIT: ST. JUDE CHILDREN’S RESEARCH HOSPITAL St. Jude Children’s Research Hospital immunologists have identified how immune sensors in infected cells organize and launch a multi-faceted innate immune response to infections with live viruses...
by Jacqueline Mitchell, Beth Israel Deaconess Medical Center Credit: Pixabay/CC0 Public Domain In the three months since Johnson & Johnson’s COVID-19 vaccine received emergency use authorization from the U.S. Food and Drug Administration, more than 10 million Americans have received the vaccine, according to the Centers for Disease Control and Prevention. The single-shot viral vector vaccine—developed...
by Sarah McDonnell, Massachusetts Institute of Technology Antigen peptides (green) from the novel albumin-binding vaccine (amphiphile, right column) were better retained in the lungs and draining lymph nodes of mice than the control vaccine (soluble, left column). Credit: Rakhra et al., Sci. Immunol. 6, eabd8003 (2021) Many viruses infect their hosts through mucosal surfaces such as...
by Ingrid Fadelli , Medical Xpress Human Embryo. Credit: Ed Uthman, MD/Wikipedia Past research has often highlighted the effects that immune activation in pregnant women can have on the development of human embryos, for instance increasing the risk of a child developing psychiatric disorders later in life. The neural mechanisms underpinning these effects, however, remain largely unclear....
