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Immune sensor ZBP1 links interferon treatment and dangerous inflammatory cell death during COVID-19
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Immune sensor ZBP1 links interferon treatment and dangerous inflammatory cell death during COVID-19

by St. Jude Children’s Research Hospital, Medical Xpress Scientists from St. Jude Children’s Research Hospital have shown that the innate immune sensor, ZBP1, and its associated inflammatory cell death pathway, PANoptosis, are major contributors to the negative effects of interferon treatment and high interferon levels in some COVID-19 patients. For viral infections, interferon therapy is...