Tag: <span>Immune Suppression</span>

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Revising theory of cancer-induced immune suppression
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Revising theory of cancer-induced immune suppression

by Will Doss,  Northwestern University Glioblastoma. Brown staining indicates IDO expression. Credit: Northwestern University Many cancers produce an enzyme called IDO that suppresses immune system activity, but the long-held hypothesis of how this mechanism operates requires revision, according to a study published in Clinical Cancer Research. In addition to engaging tryptophan metabolism, IDO enhances immunosuppressive factors of the...

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Ludwig Scientists Discover Complex Axis of Immune Suppression Exploited by Cancers

A Ludwig Cancer Research study has uncovered a new mechanism by which cancer cells evade destruction by the immune system. The paper, led by Camilla Jandus of the Lausanne Branch of the Ludwig Institute for Cancer Research, describes how immune cells known as group 2 innate lymphoid cells (ILC2s) are recruited by leukemic cells to...

September 26, 2017September 26, 2017by In Cancer