RUSH UNIVERSITY MEDICAL CENTER A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice. In a study published in the Journal of Neuroimmune Pharmacology, mouse models with COVID-19 showed positive results when a small peptide was introduced nasally. The peptide proved effective in reducing fever, protecting...
Tag: <span>Immune system</span>
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The immune system mounts a lasting defense after recovery from COVID-19
As the number of people who have fought off SARS-CoV-2 climbs ever higher, a critical question has grown in importance: How long will their immunity to the novel coronavirus last? A new Rockefeller study offers an encouraging answer, suggesting that those who recover from COVID-19 are protected against the virus for at least six months,...
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Immune system killer cells controlled by circadian rhythms
by Rensselaer Polytechnic Institute Macrophages, the killer cells of our immune system, are controlled by circadian rhythms, but the timing appears to rely upon an unexpected influence. Credit: Rensselaer Polytechnic Institute An analysis of an exhaustive dataset on cells essential to the mammalian immune system shows that our ability to fight disease may rely more heavily...
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Lilly hails Alzheimer’s win with donanemab, boasting ‘significant slowing of decline’
by Ben Adams | Jan 11, 2021 7:55am The amyloid theory continues to grasp at life as Eli Lilly has unveiled new phase 2 data from donanemab that show it can help Alzheimer’s disease patients by clearing these plaques out of the brain. Lilly’s donanemab (once known as LY3002813), works an active immunotherapy designed to stimulate the patient’s...
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New findings help explain how COVID-19 overpowers the immune system
by University of Southern California Colorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19. Credit: NIAID Integrated Research Facility, Fort Detrick, Maryland. Seeking to understand why COVID-19 is able to suppress the body’s immune response, new research from the USC Leonard Davis School of Gerontology suggests that mitochondria are one...
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A new way to help the immune system fight back against cancer
Scientists at the University of Wisconsin School of Medicine and Public Health are breaking new ground to make cancer cells more susceptible to attack by the body’s own immune system. Working in mice, a team led by Jamey Weichert, professor of radiology, and Zachary Morris, professor of human oncology, is combining two different techniques in its approach,...
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Do tumors stiff-arm the immune system?
INSIDEOUTBIO IMAGE: IMMUNE CELLS NEED TO BE CLOSE ENOUGH TO A TUMOR (WITHIN 150 Å) FOR A SYNAPSE TO FORM AND FOR THEM TO UNDERGO ACTIVATION. TUMORS USE THE EXTENDED FORM OF COMPLEMENT RECEPTOR 3 (CR 3) AND THE “I BELONG” TAB IC3B TO KEEP IMMUNE CELLS AT A DISTANCE. CREDIT: ALAN HERBERT In a...
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For people with certain BRCA mutations, activating the immune system could be promising treatment
MEMORIAL SLOAN KETTERING CANCER CENTER Treatments that harness the immune system to fight cancer have greatly improved outcomes for some people with cancer. Scientists are learning more about why some people respond much better than others to these drugs. One major factor is something called tumor mutation burden (TMB) — the number of DNA changes...
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City of Hope developed cancer-killing virus: activates immune system against colon cancer
CITY OF HOPE DUARTE, Calif. — A cancer-killing virus that City of Hope scientists developed could one day improve the immune system’s ability to eradicate tumors in colon cancer patients, reports a new study in Molecular Cancer Therapeutics, a journal of the American Association for Cancer Research. The preclinical research is a first step to showing that City of...
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Study is the first to link microbiota to dynamics of the human immune system
by Memorial Sloan Kettering Cancer Center (From left) Researchers Emily Fontana, Luigi Amoretti, Joao Xavier, Roberta Wright, and Jonas Schluter in the lab. Credit: Memorial Sloan Kettering Cancer Center Memorial Sloan Kettering Cancer Center researchers have uncovered an important finding about the relationship between the microbiota and the immune system, showing for the first time that...