MAYO CLINIC ROCHESTER, Minn. ― Adding messenger RNA, or mRNA therapy improves the response to cancer immunotherapy in patients who weren’t responding to the treatment, Mayo Clinic research shows. Immunotherapy uses the body’s immune system to prevent, control, and eliminate cancer. The study is published in Cancer Immunology Research, a journal of the American Association...
Tag: <span>Immune system</span>
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A new vaccine that alters senescent cells in a way that pushes the immune system into removing them
by Bob Yirka, Medical Xpress Fig. 1: GPNMB is a potential candidate of seno-antigen. Credit: DOI: 10.1038/s43587-021-00151-2 A team of researchers affiliated with a large number of institutions in Japan has developed a vaccine that tricks the immune system into removing senescent cells. In their paper published in the journal Nature Aging, the group describes...
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COVID-19 Breakthrough: Scientists Discover How the SARS-CoV-2 Virus Evades Our Immune System
By GRACIE BLACKWELL, TEXAS A&M COLLEGE OF MEDICINE DECEMBER 8, 2021 The expression of the immune response gene ??NLRC5 (red purple) is suppressed in SARS-CoV-2 (green) infected cells. Credit: Koichi Kobayashi A discovery by researchers at the Texas A&M College of Medicine could lead to new therapies to prevent the virus from proliferating in the human body....
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Immune system-stimulating nanoparticle could lead to more powerful vaccines
by Massachusetts Institute of Technology Credit: Pixabay/CC0 Public Domain A common strategy to make vaccines more powerful is to deliver them along with an adjuvant—a compound that stimulates the immune system to produce a stronger response. Researchers from MIT, the La Jolla Institute for Immunology, and other institutions have now designed a new nanoparticle adjuvant that...
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Research in mice shows how diet alters immune system function through a gut microbe
by Harvard Medical School Credit: Pixabay/CC0 Public Domain The cliché “you are what you eat” has been used for hundreds of years to illustrate the link between diet and health. Now, an international team of researchers has found the molecular proof of this concept, demonstrating how diet ultimately affects immunity through the gut microbiome. The work,...
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Scientists discover sugar molecule on HIV-infected cell plays role in evading immune system
by The Wistar Institute HIV-1 Virus. Credit: J Roberto Trujillo/Wikipedia A new study by researchers at The Wistar Institute, an international biomedical research leader in cancer, immunology, infectious disease, and vaccine development, shows how key features on the surface of HIV-infected cells help the disease evade detection by the immune system. It also shows how these...
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Immune system early responder can combat COVID-19
by Bill Hathaway, Yale University Credit: Pixabay/CC0 Public Domain A simple RNA molecule jumpstarts the immune system’s “first responders” to viral infection and can even eradicate the SARS-CoV-2 virus in mice with chronic cases of COVID-19, a new Yale School of Medicine study finds. The molecule, known as SLR14, is a simple, easy to manufacture, loop...
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How COVID-19 alters the immune system
by Ludwig Maximilian University of Munich Dendritic cell. Credit: D. Dudziak COVID-19 reduces the numbers and functional competence of certain types of immune cells in the blood, say LMU researchers. This could affect responses to secondary infections. The SARS-CoV-2 coronavirus causes moderate to severe disease in 3–10% of those infected. In such cases, the immune system...
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Understanding how our gut microbiome communicates with our immune system
by University of Bath Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 An international team of scientists has identified a new connection between certain molecules produced by the microbiome and the function of a protein that impacts gut inflammation. This finding takes researchers from...
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Immune system keeps the intestinal flora in balance
Trillions of benign bacteria live in the intestine. They are kept in a continuous balance by the immune system, which thereby makes them harmless to humans. Researchers in the Department for BioMedical Research (DBMR) at the University of Bern and Inselspital, Bern University Hospital, and German Cancer Research Center have been able to show how...