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Immune therapy targets cells that cause leukemia relapse
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Immune therapy targets cells that cause leukemia relapse

by Weill Cornell Medical College Credit: CC0 Public Domain Genetically engineered immune cells successfully target the specific cancer cells that may be responsible for relapse of acute myeloid leukemia (AML), a type of blood cancer, and proved effective in animal models of the disease, according to a preclinical study by investigators at Weill Cornell Medicine....

How immune cells activate the killer mode
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How immune cells activate the killer mode

UNIVERSITY OF FREIBURG FROM LEFT: SUSANA MINGUET, WOLFGANG SCHAMEL, FREDERIKE HARTL. view more CREDIT: PHOTO: LAURENZ HERR, ANJA SCHWÄBLE Unraveling a key motif: The T lymphocytes of the immune system work to destroy infected cells or cancer cells. To do so, they have to identify the threat: Molecules perceived as foreign – so-called antigens –...

Some COVID-19 patients stricken by Guillain-Barre syndrome
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Some COVID-19 patients stricken by Guillain-Barre syndrome

by E.j. Mundell, Healthday Reporter (HealthDay)—Studies are beginning to show that, in rare cases, people with severe COVID-19 may develop the serious nervous system disorder known as Guillain-Barre syndrome. “Guillain-Barre syndrome is a well-known condition in which one’s immune system targets peripheral nerves as foreign and attacks them, resulting in the cardinal features of the...

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Bacteria in pneumonia attack using bleaching agent

UMEA UNIVERSITY Research shows that bacteria use hydrogen peroxide to weaken the immune system and cause pneumonia. This according to a study at Umeå University and Stockholm University, Sweden. Hydrogen peroxide is also known as a bleaching agent that is used to whiten teeth or hair, as a stain remover, as well as for cleaning...

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Gene signature discovery may predict response to immune therapy

(TORONTO, Canada, Nov. 8, 2018) – Scientists led by Dr. Daniel De Carvalho at Princess Margaret Cancer Centre have discovered a gene signature biomarker that may predict which patients will respond – or not – to immune therapy. The findings are published online today in Nature Communications (doi: 10.1038/s41467-018-06654-8). Dr. De Carvalho, principal investigator, says...

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Possible new immune therapy target in lung cancer

Fluorescence microscopy images of blood vessels supported by perivascular cells. The top row shows vessels with perivascular cells from normal lung tissue compared to vessels supported by tumor-derived perivascular cells (bottom row). The …more   A study from Bern University Hospital in collaboration with the University of Bern shows that so-called perivascular-like cells from lung tumors...

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Inhibitors support immune therapy for leukemia

Bone marrow aspirate showing acute myeloid leukemia. Several blasts have Auer rods.   New immune therapies are considered a promising lead for treating recurring acute myeloid leukemia (AML). Antibodies are able to eliminate even those cancer cells that cannot be removed via regular therapies. Scientists from the German Cancer Consortium (DKTK) and the Munich University...