Reviewed by James Ives, M.Psych. (Editor) Axial spondyloarthritis (axSpA) is a chronic systemic rheumatoid-inflammatory disease associated with inflammation of the spine. “The affected patients often have been experiencing spinal pain since early adulthood”, EULAR President Professor Dr Iain B. McInnes, Director of the Institute of Infection, Immunity & Inflammation, The University of Glasgow, Scotland, explains:...
Tag: <span>Immunity</span>
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Five things you need to know about: mRNA vaccines
The race for a vaccine against the novel coronavirus, or SARS-CoV-2, is on, with 54 different vaccines under development, two of which are already being tested in humans, according to the World Health Organization. And among the different candidates is a new player on the scene – mRNA vaccines. One mRNA vaccine developed by US...
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Spatial mapping method pinpoints potential new therapeutic targets in lupus
by Children’s Hospital of Philadelphia A team of researchers from Children’s Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders. The findings were published...
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New vaccine holds promise in fighting diarrheal disease
OHSU research targets disease afflicting millions in developing world OREGON HEALTH & SCIENCE UNIVERSITY Scientists at Oregon Health & Science University have teamed up with OHSU spinoff, Najít Technologies, Inc. to develop a new vaccine that appears to confer immunity to a diarrheal disease that afflicts hundreds of millions of people in developing countries around...
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New drug candidate reawakens sleeping HIV in hopes of functional cure
by Sanford Burnham Prebys Medical Discovery Institute Scientists at Sanford Burnham Prebys Medical Discovery Institute have created a next-generation drug called Ciapavir (SBI-0953294) that is effective at reactivating dormant human immunodeficiency virus (HIV). The research, published in Cell Reports Medicine, aims to create a functional HIV cure by activating and then eliminating all pockets of...
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Common childhood vaccine might prevent severe complications of COVID-19
New Orleans, LA – A paper published by Paul Fidel, Jr., PhD, Professor and Director of the Center of Excellence in Oral and Craniofacial Biology and Associate Dean for Research at LSU Health New Orleans School of Dentistry, and Mairi Noverr, PhD, Professor of Microbiology & Immunology at Tulane University School of Medicine in New...
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SARS-CoV-2: New insights on antibody testing and RNA testing
Washington, DC – June 20, 2020 – Two types of tests are used to track SARS-CoV-2. Reverse transcriptase PCR (rt-PCR) tests for current infection. Antibody tests reveal that an infection has taken place, even long after the fact. Each of 2 papers published in the Journal of Clinical Microbiology (JCM) addresses one of these testing...
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Renewed hope for treatment of pain and depression
by Luxembourg Institute of Health Researchers at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) have developed LIH383, a novel molecule that binds to and blocks a previously unknown opioid receptor in the brain, thereby modulating the levels of opioid peptides produced in the central nervous system (CNS) and potentiating...
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Coronavirus antibodies may last only two to three months after infection, study suggests
Berkeley Lovelace Jr. @BERKELEYJR Coronavirus antibodies may last only two to three months after a person becomes infected with Covid-19, according to a new study published Thursday in Nature Medicine. Researchers in the Wanzhou District of China compared the antibody response of 37 asymptomatic people with that of 37 symptomatic people. The researchers found people...
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Immune cell discovery could improve the fight against hepatitis B
by Westmead Institute for Medical Research PhD student Ratna Wijaya, Professor Golo Ahlenstiel and Dr Scott Read. Credit: The Westmead Institute for Medical Research (WIMR) For the first time, researchers at The Westmead Institute for Medical Research (WIMR) have identified and described a new and unique subset of human cells that are involved in the...