Granulocyte colony-stimulating factor (G-CSF) has a significant regulatory effect not only on innate, but also on adaptive immunity. IMMANUEL KANT BALTIC FEDERAL UNIVERSITY Granulocyte colony-stimulating factor (G-CSF), which causes division and differentiation of bone marrow cells depending on the body’s need for leukocytes, has a significant regulatory effect not only on innate, but also on...
Tag: <span>Immunity</span>
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Immune system upgrade
Catalytic immunotherapy for cancer: nanoparticles act as artificial enzymes WILEY Theoretically, our immune system could detect and kill cancer cells. Unfortunately, tumors are well armed to fight these attacks. Despite modern cancer treatments, metastases and relapses remain a major problem. Increasing anti-tumor immunity might now be made possible, thanks to copper telluride nanoparticles that mimic...
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Microbiome: Untapped source of novel antimicrobials
by Delthia Ricks , Medical Xpress Just as Gold Rush prospectors once mined the Northern California hills for the shiny precious metal, “bioprospectors” are searching for a new prize: potential antimicrobial molecules—and they are hunting them down in the human microbiome. For nearly two decades scientists have been lifting the veil of mystery from the...
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The night gardeners: Immune cells rewire, repair brain while we sleep
UNIVERSITY OF ROCHESTER MEDICAL CENTER Science tells us that a lot of good things happen in our brains while we sleep – learning and memories are consolidated and waste is removed, among other things. New research shows for the first time that important immune cells called microglia – which play an important role in reorganizing...
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Study fingers new player in cancer immunity
Deleting immune-regulatory gene boosted tumor-fighting capacity in the immune cells of mice with colon cancer, melanoma HARVARD MEDICAL SCHOOL The immune system must strike an exquisite balance between vanquishing infections and cancer, while at the same time restraining its activity to avoid inadvertently attacking the body’s healthy tissues and organs. This balancing feat is accomplished by...
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Q&A: Should you get vaccinations with a suppressed immune system?
by Mayo Clinic News Network Dear Mayo Clinic: I am 72 and take a drug for rheumatoid arthritis that suppresses my immune system. I’m scheduled to receive a vaccine later this year. Is it safe for me to receive this vaccine? A: Appropriate and timely vaccines are important for anyone with a suppressed immune system....
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Striking a balance: a mechanism to control autoimmunity
by Research Institute of Molecular Pathology B cells are white blood cells that generate antibodies against an almost unlimited number of pathogens, a capacity that is vital for any higher organism. However, establishing a diverse repertoire of pathogen recognition comes at a price, as some B cells will inevitably go wild and turn against the...
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Blocking a hormone’s action in immune cells may reduce heart disease risk
by American Physiological Society Blocking the mineralocorticoid receptor (MR)—a protein that helps maintain normal levels of salt and water in the body—in immune cells may help reduce the risk of heart attack and stroke by improving blood vessel health. The study will be presented today at the American Physiological Society (APS) Aldosterone and ENaC in...
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Human kidney map charts our growing immune defense
New cell atlas reveals immune cells present in zones of human kidney WELLCOME TRUST SANGER INSTITUTE The first cell atlas of the human kidney’s immune system has been created after scientists mapped nearly 70,000 individual kidney cells from early life and adults. Researchers at the Wellcome Sanger Institute, University of Cambridge, Newcastle University and their...
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Mumps study shows immunity gaps among vaccinated people
Posted Today Immunity against mumps virus appears insufficient in a fraction of college-aged people who were vaccinated in childhood, research from Emory Vaccine Center and the Centers for Disease Control and Prevention indicates. The findings highlight the need to better understand the immune response to mumps and mumps vaccines. The results of the study are...