MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS IMAGE: EXAMPLE OF A GENE THAT CONTAINS TWO POSSIBLE START SITES (TSS), AND TWO POSSIBLE END SITES (TES). BLACK BOXES IN THE GENE MODEL SHOW SEQUENCES THAT WILL BE TRANSLATED INTO PROTEIN. WITH CONVENTIONAL SHORT-READ MRNA SEQUENCING, IN WHICH SIGNAL REPRESENTS THE ACCUMULATION OF READS, IT IS NOT...