by NIH/National Institute of Allergy and Infectious Diseases Transmission electron micrograph of SARS-CoV-2 virus particles (gold) within endosomes of a heavily infected nasal epithelial cell. Credit: NIAID In adults who had previously received a full regimen of any of three COVID-19 vaccines granted Emergency Use Authorization (EUA) or approved by the Food and Drug Administration...
By Dr. Tomislav Meštrović, MD, Ph.D. A new study published on the preprint server medRxiv* by a research group from the U.S. and Germany indicates that a novel BNT162b1 RNA-based vaccine against coronavirus disease (COVID-19) induces functional and proinflammatory T cell responses in almost all participants – marking another landmark achievement for this promising vaccine...
Trends The ER is a key organelle in cell physiology, and it evolved as an elaborated signaling pathway to cope with life-threatening perturbations of its homeostatic state. This process, called the UPR, is exploited by cancer cells to survive in their microenvironment and to promote tumor progression. Many approaches have been investigated to inhibit or...
