Research team from Göttingen and Halle develops new inhibitors for enzymes PROTEIN CRYSTALS OF THE HUMAN ENZYME GLUTAMINYL CYCLASE AND ATOMIC STRUCTURE OF THE NEW INHIBITOR. view more CREDIT: LISA-MARIE FUNK With over 1.2 million people affected in Germany alone and over 50 million people worldwide, Alzheimer’s disease, also referred to simply as Alzheimer’s, is...
by Perelman School of Medicine at the University of Pennsylvania Researchers from the Penn Institute of Immunology discovered three distinct immune responses to the SARS-CoV2 infection that could help predict the trajectory of disease in severe COVID-19 patients and may ultimately inform how to best treat them. The findings were published in Science. “For patients...
by Johns Hopkins University Bloomberg School of Public Health Strains of a common subtype of influenza virus, H3N2, have almost universally acquired a mutation that effectively blocks antibodies from binding to a key viral protein, according to a study from researchers at Johns Hopkins Bloomberg School of Public Health. The results have implications for flu...
by University of Helsinki Activating the immune system is a promising form of cancer treatment. Researchers at the University of Helsinki and Helsinki University Hospital as well as the University of Eastern Finland mapped out the immune landscape of hematological malignancies in a dataset covering more than 10,000 patients to identify drug targets and patient...
So far there are no approved drugs for Non-Alcoholic Fatty Liver Disease UNIVERSITY OF COLORADO ANSCHUTZ MEDICAL CAMPUS AURORA, Colo. (July 8, 2020) – In an effort to combat a growing worldwide epidemic of Nonalcoholic Fatty Liver Disease (NAFLD), scientists have discovered a new target and a new therapy that has shown promising results in...
Asthma does not seem to increase the risk of a person contracting COVID-19 or influence its severity, according to new research. Researchers say further study is needed but those with the chronic respiratory disease don’t appear to be at a higher risk of getting extremely ill or dying from coronavirus. “Older age and conditions such...
by La Jolla Institute for Immunology Flashback to mid-March: the novel coronavirus had reached San Diego, California. Few people could get tested, and even less was known about how the virus mutated as it spread from person to person. Scientists now know that two variants of the novel coronavirus (SARS-CoV-2) were circulating at that time....
Inaccurate: RNA from a vaccine would not be able to directly alter our DNA, in part because of the chemical differences between the two nucleic acids. RNA also would not persist long enough to cause autoimmunity. Autoimmune diseases are chronic in nature, whereas RNA has a very short lifespan, being quickly degraded after it has...
by Brian Burns, Massachusetts General Hospital Hospitalized patients who report an allergy to penicillin are often prescribed alternative antibiotics for infection that can be harmful, even though diagnostic testing or evaluations would show that the vast majority of these reported allergies could be disproven, according to researchers from Massachusetts General Hospital. In a national study...
by Osaka University Tet-mediated B cell tolerance Tet2/3-deficient B cells are activated by self-antigen and express exaggerated amount of CD86. Then those B cells stimulate autoreactive CD4+ T cells, resulting in autoimmune response. Credit: Osaka University The immune system is supposed to protect from external microbial invaders, but sometimes it turns its efforts inward, potentially...
