Stool microbes make a challenging diagnosis easier SCHEMATIC SHOWING HOW THE MICROBIOME SIGNATURE FROM STOOL SAMPLES CAN BE USED TO TEST FOR CIRRHOSIS. view more CREDIT: SALK INSTITUTE LA JOLLA–(July 1, 2020) Chronic liver disease represents a major global public health problem affecting an estimated 844 million people, according to the World Health Organization. It...
ATLANTA – Researchers at the Yerkes National Primate Research Center and the Emory Vaccine Center (EVC) are first to show a new adjuvant, 3M-052, helps induce long-lasting immunity against HIV. The study results are published today in Science Immunology. In this pre-clinical study that included 90 rhesus monkeys, the researchers showed 3M-052, a new, synthetic...
become T follicular helper cells (Tfh cells, shown in blue), which work with B cells (shown in green) to produce powerful antibodies. Activated B cells give rise germinal centers (shown in red), where mature B cells proliferate and produce highly specific antibodies against pathogens. Bcl6 blocks the expression of two proteins that normally stop Tfh...
A recent study led by Texas Tech’s Department of Biological Sciences and Natural Science Research Laboratory determined that certain genes are associated with the pathogens that infect chronic wounds and hinder the healing process. CALEB PHILLIPS; ASSISTANT PROFESSOR OF BIOLOGICAL SCIENCES AND DIRECTOR OF THE PHILLIPS LABORATORY, COLLEGE OF ARTS & SCIENCES; CURATOR OF GENETIC...
by Deborah Kotz, University of Maryland School of Medicine Researchers at the University of Maryland School of Medicine (UMSOM) evaluated several human antibodies to determine the most potent combination to be mixed in a cocktail and used as a promising anti-viral therapy against the virus that causes COVID-19. Their research, conducted in collaboration with scientists...
A study of 149 people who have recovered from COVID-19 show that although the amount of antibodies they generated varies widely, most individuals had generated at least some that were intrinsically capable of neutralizing the SARS-CoV-2 virus. The findings are published in the journal Nature. Antibodies vary widely in their efficacy. While many may latch...
Chemical compound restores tetracycline’s effectiveness by blocking bacterial resistance. The latest generation of tetracyclines — a class of powerful, first-line antibiotics — was designed to thwart the two most common ways bacteria resist such drugs. But a new study from researchers at Washington University in St. Louis and the National Institutes of Health (NIH) has...
Ingrid Hein June 18, 2018 AMSTERDAM — A blood test for people at risk for rheumatoid arthritis can identify those who will develop the disease within 3 years, new research shows. “Our data support a new biomarker that demonstrates better predictive power than other biomarkers evaluated so far,” said investigator Anne Musters, MD, from the...
by Sarah Avery, Duke University As many people know, bladder infections can be a painful and recurring condition, and those who are prone to the infections often report they have to “go” with greater frequency and urgency. These two related conditions are caused by an aberrant immune response that prioritizes repairing tissue in the bladder...
by Brian Burns, Massachusetts General Hospital Results from a study led by investigators at Massachusetts General Hospital may help to improve the diagnosis and treatment of allergies, pointing to a potential marker of these conditions and a new therapeutic strategy. The research is published in Nature. Nearly one third of the world’s population suffers from...
