by University of Barcelona Credit: Journal of Clinical Investigation Insight (2024). DOI: 10.1172/jci.insight.163359. https://insight.jci.org/articles/view/163359Parkinson’s disease is one of the most common diseases affecting the motor and nervous system. It has no treatment yet, and the pathology causes a deterioration of motor skills due to dopaminergic neuronal death, the neurons that synthesize dopamine, which is a brain...
by Duke University Duke University researchers have developed a synthetic molecule that selectively dampen the physiological rewards of cocaine in mice. It also may represent a new class of drugs that could be more specific with fewer side effects than current medications. In mice that were treated with the stimulant cocaine or methamphetamine, the new...
Of all the hepatitis viruses, D is the most poorly known. This small virus, which can only infect people already infected with Hepatitis B, has so far been little studied. Hepatitis D is one of the most dangerous forms of chronic viral hepatitis because of its possible progression to irreversible liver diseases (cancer and cirrhosis, in particular)....
Durham, NC – A new study released today in STEM CELLS suggests for the first time that regulatory T-cells (Treg) induced by mesenchymal stromal cells can yield an abundant replacement for naturally occurring T-cells, which are vital in protecting the body from infection. Led by Rita I. Azevedo, Ph.D., at the Instituto de Medicina Molecular...
Immune cells called inflammatory monocytes are often one of the first responders to infections, but they actually facilitate the progression of Cryptococcus neoformans infection in mice, according to a study published March 21 in the open-access journal PLOS Pathogens by Lena Heung and Tobias Hohl of Memorial Sloan Kettering Cancer Center. According to the authors, these disparate results indicate that inflammatory monocytes possess a plasticity of...
