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New immunotherapy drugs target two evasive cancer-driving proteins
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New immunotherapy drugs target two evasive cancer-driving proteins

By Jocelyn Kaiser Mar. 1, 2021 , 11:00 AM Researchers have shown in mice that designer antibodies can curb the growth of tumors by targeting two of cancer’s most infamous offenders—the proteins RAS and p53, which are mutated in many tumors but have largely defied drug development efforts. If their promise holds up in clinical trials,...

Breast cancer-on-a-chip for testing immunotherapy drugs
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Breast cancer-on-a-chip for testing immunotherapy drugs

TERASAKI INSTITUTE FOR BIOMEDICAL INNOVATION IMAGE: BREAST CANCER CHIP CREDIT: KHADEMHOSSEINI LAB (LOS ANGELES) – There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called “checkpoint proteins.” These checkpoint proteins bind to...