Tag: <span>Immunotherapy</span>

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Immunotherapy for lung cancer: What you need to know

Immunotherapy, also known as biologic therapy, may benefit people fighting certain kinds of lung cancer. This treatment option uses medicines to stimulate the body’s immune system so that it can fight the cancer cells more effectively. Immunotherapy has changed the way doctors treat many types of cancer, including lung cancer. In this article, we look at how immunotherapy...

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Immunotherapy treatment option for selected breast cancer patients, genetic study suggests

Immunotherapy drugs could help some breast cancer patients based on the genetic changes in their tumours, researchers at the Wellcome Trust Sanger Institute and their collaborators find. Published today (13 September) in Cancer Research, scientists identify particular genetic changes in a DNA repair mechanism in breast cancer. The results open up the possibility to another therapy...

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Researchers discover new immunotherapy combination effective at killing cancer cells

Immunotherapy is an emerging field in the global fight against cancer, even though scientists and clinicians have been working for decades to find ways to help the body’s immune system detect and attack cancerous cells. Doug Mahoney’s lab at the University of Calgary recently discovered an immunotherapy that uses existing cancer drugs in a whole...

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CNIC scientists find the key to improved cancer immunotherapy

The study, published in Nature Communications, demonstrates that tissue-resident and circulating memory T cells cooperate in anti-tumor immunity Researchers at the Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) have investigated how different subtypes of essential immune-response cells called CD8+ T lymphocytes cooperate to mount a stronger anti-tumor response. The results show that generation of...

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Barrier proteins in tumors are possible key to immunotherapy success

By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs. The “proof of concept” findings, published online Feb. 13,...

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Immunotherapy for prostate cancer: What you need to know

Prostate cancer is one of the most common forms of cancer in American men. The condition affects 1 in 7 men during their lifetime, according to the American Cancer Society. Traditional treatments for prostate cancer include surgery, chemotherapy, and radiation. However, there are emerging therapies that have shown promise in treating prostate cancer. An example is immunotherapy. Immunotherapy is a...

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Immunotherapy kinder than chemotherapy for patients with head and neck cancer

The immunotherapy nivolumab is kinder than chemotherapy for people with advanced head and neck cancer – easing many of the negative effects of the disease on patients’ quality of life. Both head and neck cancer and the treatment for it can have a huge impact on patients – affecting their speech, breathing, eating and drinking,...

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Researchers chart pathway to ‘rejuvenating’ immune cells to fight cancers and infections

St. Jude Children’s Research Hospital immunologists have discovered how immune cells called T cells become “exhausted”—unable to do their jobs of attacking invaders such as cancer cells or viruses. The finding is important because patients treated with immunotherapies against cancers are often non-responsive or experience a relapse of their disease, and it has been suggested...

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A lead candidate for immunotherapy may increase tumour growth in certain cancers

  Boosting a part of the immune system known to have anti-tumour properties may actually help tumours grow in cancers linked to chronic inflammation. Cancer immunotherapies boost aspects of the body’s normal immune system, to help fight tumours. They are part of a fast-evolving field of research and medicine, with several types of immunotherapies currently...

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Some lung cancer patients benefit from immunotherapy even after disease progression

Some advanced lung cancer patients benefit from immunotherapy even after the disease has progressed as evaluated by standard criteria, according to research presented at the European Lung Cancer Conference (ELCC).1 The findings pave the way for certain patients to continue treatment if the disease is not progressing according to new, more specific, criteria. The Response Evaluation...