Tag: <span>induced pluripotent stem cell (iPSC)</span>

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iPSC-Derived Retina Transplants Improve Vision in rd1 End-Stage Retinal-Degeneration Mice

Highlights iPSC retina reconstructs outer nuclear layer in the end-stage retina Contacts between the host bipolar cells and graft photoreceptors were visualized rd1 mice became responsive to light after iPSC-retina transplantation RGC responses to light were recorded from host rd1 retina after transplantation Summary Recent success in functional recovery by photoreceptor precursor transplantation in dysfunctional retina has led...