A new drug regimen requiring injections every eight weeks have shown to be more effective in preventing HIV infection than one in which a pill must be taken daily, researchers from the HIV Prevention Trials Network (HPTN) announced at the 23rd International AIDS Conference. Emory University was a key participant in the study, enrolling seven...
Dive Brief: India’s drug regulator has granted an emergency approval to the antibody drug itolizumab to treat the potentially deadly immune response, cytokine release syndrome, that appears to affect some patients hospitalized with acute respiratory distress related to COVID-19. The Drugs Controller General of India cleared the treatment for use after itolizumab, alongside standard of...
by University of York Targeting the Trypanosoma brucei cell cycle: the target represents the compound AB1, and (the dart) its phenotype showed as a parasite with cell cycle defects. Credit: Manuel Saldivia and Andrés Sánchez Scientists say they are a step closer to developing a drug to kill the trypanosome parasite that causes human African...
Nature wades through the literature on the new coronavirus — and summarizes key papers as they appear. 10 July — Massive contact-tracing effort finds hundreds of cases linked to nightclubs Mobile phone and credit card data helped to identify nearly 250 coronavirus infections linked to a fast-moving outbreak that began in a popular nightclub district...
by BioMed Central Human papilloma viruses (HPVs) – a common group of viruses known to cause cervical cancers—may also have a causal role in prostate cancer, according to a literature review published in the open access journal Infectious Agents and Cancer, supporting the case for universal HPV vaccination. James Lawson and Wendy Glenn, at the...
Inhale, exhale. Humans breathe between 17,000 to 23,000 times a day, on average. But for more than 70,000 children and young adults around the world, taking a breath can be a struggle because of a rare disease, cystic fibrosis. A gene that normally triggers a certain protein to move chloride, found in salt, to cell...
by Doherty Institute for Infection and Immunity Scientists have uncovered how a crucial component of the immune system responds to the spike protein of SARS-CoV-2, the virus that causes COVID-19—important information for future validation of vaccine candidates. Coronavirus particles have a corona (crown) of proteins that resemble spikes, which enable the virus to attach and...
Researchers have developed a way to pull HIV out of the latent reservoir making the virus visible to the immune system and providing the potential to be killed by treatment. Part of what has made HIV infection so difficult to cure, is that once the virus enters the body, some of it hides dormant inside...
A new coronavirus test can detect past and present COVID-19 infections in just 20 minutes. The Independent reported that blood samples were used by Australian researchers in their newly developed COVID-19 test to determine novel coronavirus infections in 20 minutes; they claimed that is is a world-first breakthrough. Past and Present COVID-19 Infection Can Now...
Context and Significance Respiratory viral diseases, such as seasonal influenza or COVID-19, are deadly scourges on society. Immunometabolic therapies may be important tools to reduce the burden of death and long-term disability caused by pandemic viruses. Here, we describe the biological effects of ketone bodies, natural metabolites produced during fasting or carbohydrate restriction, that maintain...
