Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids (OxPL), molecules on cell surfaces that get modified by inflammation. Even while on a high-fat diet, the antibody protected the mice from arterial plaque formation, hardening of the...
Tag: <span>inflammation</span>
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Drug reduces inflammation in stroke patients
A blood clot forming in the carotid artery. An anti-inflammatory drug given to patients in the early stages of a stroke has been shown by researchers at The University of Manchester and Salford Royal NHS Foundation Trust to reduce harmful inflammation. The drug, Kineret, licenced for treating rheumatoid arthritis, was given as a small...
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Protein Regulates Vitamin a Metabolic Pathways, Prevents Inflammation
A team of researchers from Case Western Reserve University School of Medicine have discovered how uncontrolled vitamin A metabolism in the gut can cause harmful inflammation. The discovery links diet to inflammatory diseases, like Crohn’s disease and inflammatory bowel syndromes, and could inform nutritional interventions. In the Proceedings of the National Academy of Sciences, the researchers...
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Researchers identify critical molecular link between inflammation and diabetes
High-resolution model of six insulin molecules assembled in a hexamer. A new study by researchers at the University of Maryland School of Medicine (UM SOM) has uncovered how inflammation contributes to a key feature of diabetes, the body’s inability to metabolize glucose, a condition known as insulin resistance. More than 30 million Americans suffer...
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Tantalizing Clues Point to Inflammation’s Role in an Array of Diseases
Inflammation has become one of the hottest buzzwords in medical science, pointed to as a culprit in causing or aggravating conditions ranging from allergy to autism to Alzheimer’s disease. But it’s far from clear that standard anti-inflammatory drugs, which have been around for decades, will help patients with those conditions, especially since they often come...