by University of Southern California Credit: CC0 Public Domain Inflammatory bowel disease (IBD) is a chronic condition involving inflammation of the digestive tract, affecting some 1.6 million Americans. Depression affects more than 16 million Americans. A new study from Keck Medicine of USC shows that patients diagnosed with IBD were nine times as likely to...
by Jillian Prior, Rutgers University High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia Researchers at Rutgers Robert Wood Johnson Medical School have identified immune cells in the intestine that are needed to prevent inflammatory bowel disease (IBD), colitis and Crohn’s disease, which affect 3 million people in the United States....
by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine? New research published in Science Immunology and led by investigators at Massachusetts General Hospital (MGH) indicates...
by Okayama University The new synthesis technique offers higher yields than convential methods of synthesis and also succeeded in reducing the use of organic solvents, thus making the overall process more sustainable. Credit: Hiroki Kakuta Inflammatory bowel disease (IBD), characterized by a chronic inflammation of the digestive tract, is currently treated with steroids and antibody...
by Technical University Munich Dr. Monica Yabal, research group leader at the Institute of Molecular Immunology (front), and her team have discovered how inflammatory bowel disease leads to a chain reaction that upsets the gut microbiome. Credit: Astrid Eckert / TUM Chronic inflammatory bowel disease (IBD) is becoming increasingly widespread. Until now, however, the underlying...
In response to gut inflammation, such as that caused by inflammatory bowel disease (IBD), the vascular barrier in the brain choroid plexus closes, locking down access to the brain, according to a new study. While this gut-brain vascular axis deregulation likely protects the brain from inflammation, the findings suggest it may also result in the...
by Brigham and Women’s Hospital Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 The world of microbes living in the human gut can have far-reaching effects on human health. Multiple diseases, including inflammatory bowel disease (IBD), are tied to the balance of these microbes,...
by KU Leuven Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 A method that instructs immune system cells to help repair damaged tissues in the intestine has been developed by researchers at KU Leuven and Seoul National University. This opens the way for more effective treatment...
The microbiome comprises trillions of microorganisms living on and inside each of us. Historically, some researchers have guessed at its role in human health, but in the last decade or so genetic sequencing techniques have illuminated this galaxy of microorganisms enough to study it in detail. As researchers unravel the complex interplay between our bodies and microbiomes, they are...
by Mike Addelman, University of Manchester A rare genetic condition which causes inflammatory bowel disease can be successfully treated by bone marrow transplant, according to University of Manchester and Manchester University NHS Foundation Trust researchers. The disease, called G6PC3 deficiency, affects around one in a million people and causes inflammation of the bowel, as well as lung...
