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Study points to potential new treatment for inflammatory bowel diseases
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Study points to potential new treatment for inflammatory bowel diseases

by University of Calgary Credit: Pixabay/CC0 Public Domain People with inflammatory bowel diseases develop inflammation of the intestine that can cause thickening of the gut wall and life-threatening blockage of the intestinal tube. Twenty to 50 percent of people with Crohn’s disease and ulcerative colitis are affected over their lifetime by this poorly understood condition,...

About half of patients with inflammatory bowel disease have zinc deficiency
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About half of patients with inflammatory bowel disease have zinc deficiency

The prevalence of zinc deficiency is about 50 percent in inflammatory bowel disease (IBD) and is higher in patients with Crohn disease (CD) than those with ulcerative colitis (UC), according to a study published online Sept. 29 in Nutrients. Roberta Zupo, from the National Institute of Gastroenterology “Saverio de Bellis” in Italy, and colleagues conducted a systematic...

How a Japanese herbal medicine protects the gut against inflammatory bowel disease
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How a Japanese herbal medicine protects the gut against inflammatory bowel disease

RIKEN IMAGE: THE CONDITION OF MICE WITH COLITIS IMPROVED AFTER TREATMENT WITH DAIKENCHUTO, A MEDICINE MADE FROM GINGER, GINSENG, AND JAPANESE PEPPER. ANALYSIS SHOWED THAT THIS WAS BECAUSE IT PREVENTS THE LOSS OF KEY BACTERIA IN THE GUT AND FACILITATES THE ACTIVITY OF INNATE IMMUNE CELLS IN THE GUT CALLED ILC3S. CREDIT: RIKEN Zhengzheng Shi...

Fecal transplant throws new light on inflammatory bowel disease
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Fecal transplant throws new light on inflammatory bowel disease

by University of Groningen How the adoptive transfer of altered gut microbiota is sufficient to disrupt/restore intestinal tissue homeostasis. Credit: Markus Schwalbe and Sahar El Aidy, University of Groningen Inflammatory bowel disease is accompanied by a number of changes in the intestines, such as a change in epithelial permeability, a change in the composition of...

New study shows bidirectional link between inflammatory bowel disease and depression
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New study shows bidirectional link between inflammatory bowel disease and depression

by University of Southern California Credit: CC0 Public Domain Inflammatory bowel disease (IBD) is a chronic condition involving inflammation of the digestive tract, affecting some 1.6 million Americans. Depression affects more than 16 million Americans. A new study from Keck Medicine of USC shows that patients diagnosed with IBD were nine times as likely to...

New study identifies potential treatment for inflammatory bowel disease
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New study identifies potential treatment for inflammatory bowel disease

by Jillian Prior, Rutgers University High magnification micrograph of Crohn’s disease. Biopsy of esophagus. H&E stain. Credit: Nephron/Wikipedia Researchers at Rutgers Robert Wood Johnson Medical School have identified immune cells in the intestine that are needed to prevent inflammatory bowel disease (IBD), colitis and Crohn’s disease, which affect 3 million people in the United States....

Some gut viruses promote intestinal health, while others contribute to inflammatory bowel disease
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Some gut viruses promote intestinal health, while others contribute to inflammatory bowel disease

by Massachusetts General Hospital Credit: Pixabay/CC0 Public Domain Research in recent years has demonstrated the diverse roles that gut bacteria can play in health and disease, but what about contributions from viruses, which, like bacteria, perpetually reside within the human intestine? New research published in Science Immunology and led by investigators at Massachusetts General Hospital (MGH) indicates...

Green synthesis of drug candidate for inflammatory bowel disease
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Green synthesis of drug candidate for inflammatory bowel disease

by Okayama University The new synthesis technique offers higher yields than convential methods of synthesis and also succeeded in reducing the use of organic solvents, thus making the overall process more sustainable. Credit: Hiroki Kakuta Inflammatory bowel disease (IBD), characterized by a chronic inflammation of the digestive tract, is currently treated with steroids and antibody...

Cause of inflammatory bowel disease discovered
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Cause of inflammatory bowel disease discovered

by Technical University Munich Dr. Monica Yabal, research group leader at the Institute of Molecular Immunology (front), and her team have discovered how inflammatory bowel disease leads to a chain reaction that upsets the gut microbiome. Credit: Astrid Eckert / TUM Chronic inflammatory bowel disease (IBD) is becoming increasingly widespread. Until now, however, the underlying...

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Gut-brain axis response to inflammation may underlie inflammatory bowel disease

In response to gut inflammation, such as that caused by inflammatory bowel disease (IBD), the vascular barrier in the brain choroid plexus closes, locking down access to the brain, according to a new study. While this gut-brain vascular axis deregulation likely protects the brain from inflammation, the findings suggest it may also result in the...