by Ali Howard, University of Glasgow An international team of scientists, led by the University of Glasgow, has announced findings that could pave the way to a new treatment for asthma and chronic obstructive pulmonary disease (COPD). The breakthrough findings, published today in Science Translational Medicine, identify a new class of drugs that reverse the...
By Benedette Cuffari, M.Sc. Reviewed by Emily Henderson, B.Sc. By definition, encephalitis is the inflammation of the brain. The causes of infectious encephalitis can be viral, bacterial, fungal, protozoal, or helminthic; however, about 70% of encephalitis cases are viral in etiology. Types of encephalitis Encephalitis can be characterized as either primary or secondary. Whereas primary...
by Kate Wighton, Imperial College London Micrograph showing inflammation of the large bowel in a case of inflammatory bowel disease. Colonic biopsy. Credit: Wikipedia/CC BY-SA 3.0 A new study has found one in ten people with inflammatory bowel disease visited their doctor with symptoms five years before receiving a diagnosis. Inflammatory bowel disease is a...
Tested in mice with genetically induced arthritis, the substance decreased the area affected, reduced local swelling, and assuaged the pain associated with the inflammatory process. ARTHRITIC MOUSE PAW TREATED WITH TPPU (LEFT) AND UNTREATED PAW OF ANOTHER ARTHRITIC MOUSE. By José Tadeu Arantes | Agência FAPESP – Arthritis affects almost 2% of the world’s population,...
Researchers from the Perelman School of Medicine at the University of Pennsylvania have now identified a protein called histone deacetylase 3 (HDAC3) as the orchestrator of the immune system’s inflammation response to infection. By using both specially cultured cells and small animal models, HDAC3 was found to be directly involved in the production of agents...
Drugs with neuroprotector effects UNIVERSITY OF BARCELONA FROM LEFT TO RIGHT, SANTIAGO VÁZQUEZ, CARLES GALDEANO, MERCÈ PALLÀS AND CHRISTIAN GRIÑÁN-FERRÉ (FACULTY OF PHARMACY AND FOOD SCIENCES/UNIVERSITY OF BARCELONA)…. view more CREDIT: UNIVERSITY OF BARCELONA A UB study published in the journal Neurotherapeutics has validated a new pharmacological target for Alzheimer’s disease. The results show the...
Developing a better understanding of KBTBD2 could have implications for Type 2 diabetes, UTSW researchers say UT SOUTHWESTERN MEDICAL CENTER THE ILLUSTRATION SHOWS THE IDENTIFICATION OF KBTBD2 AS A KEY GENE IN THE MAINTENANCE OF WHOLE-BODY INSULIN SENSITIVITY THROUGH ITS ROLE IN FAT. LOSS OF KBTBD2 LEADS TO THE ACCUMULATION… view more CREDIT: UT SOUTHWESTERN...
by La Jolla Institute for Immunology Scrape your knee, and you’ll see some red puffiness appear around the injury. This is inflammation, and it is driven by the immune system. Inflammation around a scrape is minor, but inflammation around joints—due to diseases like rheumatoid arthritis—can be incredibly painful. And inflammation in and around the blood...
by Thamarasee Jeewandara , Medical Xpress Optimization of microswimmer shape for targeted drug delivery. Illustration of a future use case for the medical microrobots emphasizing an important design tradeoff. Double-helical magnetic microswimmers with filled internal cores are 3D-printed as concentrated drug-carrying bodies. Three morphological derivatives of the same design are tested with the same body...
The race for a vaccine against the novel coronavirus, or SARS-CoV-2, is on, with 54 different vaccines under development, two of which are already being tested in humans, according to the World Health Organization. And among the different candidates is a new player on the scene – mRNA vaccines. According to Prof. Bekeredjian-Ding, an approved...
