by University of Bonn The host RNA is methylated by MTr1 to a mature cap1 RNA. The influenza virus snatches the cap part of the mature host RNA to start viral replication. MTr1-deficient cells or cells treated with MTr1 inhibitors do not lead to IAV replication. Credit: Yuta Tsukamoto/UKB Viruses use the molecular repertoire of...
By Michelle Franklin – [email protected] According to the World Health Organization, each year there are an estimated 1 billion cases of influenza, between 3-5 million severe cases and up to 650,000 influenza-related respiratory deaths globally. Seasonal flu vaccines must be reformulated each year to match the predominantly circulating strains. When the vaccine matches the predominant...
by Holly Ober, University of California – Riverside This digitally-colorized transmission electron microscopic image depicts the ultrastructural details of an influenza virus particle. Credit: CDC, Frederick Murphy It happens every year, especially in winter. A virus saunters into your wide-open respiratory tract, worms its way into lung cells, and, next thing you know, you’re lying...
