by William Weir, Yale School of Engineering and Applied Science Bioadhesive nanoparticles (white) after being taken up by skin cancer tumor cells during in virtro culture. Credit: Julia Lewis Yale researchers are developing a skin cancer treatment that involves injecting nanoparticles into the tumor, killing cancer cells with a two-pronged approach, as a potential alternative to surgery....
MARY ANN LIEBERT, INC./GENETIC ENGINEERING NEWS JOURNAL IN THE FIELD AND PROVIDES ALL-INCLUSIVE ACCESS TO THE CRITICAL PILLARS OF HUMAN GENE THERAPY: RESEARCH, METHODS, AND CLINICAL APPLICATIONS New Rochelle, NY, September 2, 2020—A meta-analysis of non-human primate (NHP) studies showed that adeno-associated virus (AAV) gene therapy often caused dorsal root ganglion (DRG) pathology. There were...
Combination therapy reduces tumor size, dramatically improves survival in mice NORTHWESTERN UNIVERSITY CHICAGO — When breast cancer spreads to the brain, the prognosis is grim. Patients only have about six months to live. Women with HER2-positive breast cancer tend to develop brain metastases in up to 55% of cases. Chemotherapy drugs targeting breast cancer cells...
A new leading US-based COVID-19 vaccine is set to begin its 2nd phase of testing in South Africa. The NVX‑CoV2373, made by Novavax biotechnology company, has seen improving the immune system and stimulating antibodies inside the patient. One of the major benefactors of the drug is the Bill & Melinda Gates Foundation. Here’s what it...
by University of California, Los Angeles A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it. In research published in the peer-reviewed journal Clinical Infectious Diseases,...
Experts document progress made through rehabilitation interventions that improves quality of life Experts document progress made through rehabilitation interventions that improves quality of life for patients with cerebral palsy, in this special issue of the Journal of Pediatric Rehabilitation Medicine Amsterdam, NL, August 3, 2020 – Cerebral palsy (CP) is one of the most common...
NANYANG TECHNOLOGICAL UNIVERSITY A PROTOTYPE TEMPORAL PRESSURE DEVICE DEVELOPED BY THE NTU AND A*STAR SCIENTISTS, WHICH CAN PUT PRESSURE ON THE SKIN, THUS CREATING MICROPORES THAT ALLOWS THE DRUGS TO PASS THROUGH THE… view more CREDIT: NTU SINGAPORE Scientists from Nanyang Technological University, Singapore (NTU Singapore) and the Agency for Science, Technology and Research (A*STAR)...
MIT engineers are using computing modeling to prevent microparticles from clogging during injections. Microparticles offer a promising way to deliver multiple doses of a drug or vaccine at once because they can be designed to release their payload at specific intervals. However, the particles, which are about the size of a grain of sand, can...
Type 2 diabetes is a major burden on healthcare systems in the entire world. It is especially prevalent among older men, who typically don’t follow healthy diets, don’t exercise and generally don’t take good care of themselves. Now a team of scientists led by the University of Adelaide found that two years of testosterone might...
MEDGADGET EDITORS GENETICS, NANOMEDICINE, OPHTHALMOLOGY Wet age-related macular degeneration and a number of other eye diseases, including congenital conditions, are related to mutated genes that result in blood vessel abnormalities. These can be treated with gene therapy, but delivering genetic material has proven to be difficult when dealing with large gene sequences that are common...
