by Monash University Credit: Shutterstock Monash University researchers have shown for the first time that mesenteric (gut) lymphatic dysfunction is a potential cause of and therapeutic target for obesity and insulin resistance. The groundbreaking study, published in Nature Metabolism, identified a profoundly damaging cycle in which a high fat diet promotes dysfunction of the mesenteric lymphatics, that in turn leads to...
by Max Bingham, Harvard Medical School Credit: Pixabay/CC0 Public Domain In what could be a starting point for new therapeutics to tackle insulin resistance, a major driver of type 2 diabetes and metabolic syndrome present in 20–30 percent of the general U.S. population, researchers recently found that insulin resistance in the general population seems likely to be caused...
by University of California, Los Angeles Mitochondria inside liver cells (hepatocytes). Credit: Mayuko Segawa, Liesa lab at UCLA Health A new multi-institution study led by a team of researchers at the David Geffen School of Medicine demonstrated that blocking a protein called ABCB10 in liver cells protects against high blood sugar and fatty liver disease in obese mice....
Animal studies examine risk factors that may overlap between colorectal cancer and cardiovascular disease Christian Rask-Madsen, M.D., Ph.D., is assistant investigator in the Section on Vascular Biology and Complications at Joslin Diabetes Center, and assistant professor at Harvard Medical School. Over the decades, scientists have repeatedly shown that patients with increased levels of the hormone...
