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Insulin resistance under-diagnosed in non-diabetics with Parkinson’s disease

Findings could lead to increased screening for PD patients to detect and correct insulin resistance, reports the Journal of Parkinson’s Disease IOS PRESS Amsterdam, NL, August 2, 2018 – Almost two-thirds of non-diabetic patients with Parkinson’s disease (PD) may be insulin resistant, despite having normal blood sugar, report scientists in the Journal of Parkinson’s Disease. Their findings suggest...

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Keto diet: Scientists find link to diabetes risk

By finding a link to a condition that raises the risk of type 2 diabetes, new research questions the health benefits of ketogenic diets. Is there a link between diabetes and the keto diet? Ketogenic diets are low-carbohydrate, high-fat diets that have been shown to reduce weight. They change metabolism so that energy comes from...

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Human insulin as safe and effective to treat type 2 diabetes as costlier insulin analogs

Patients with Type 2 diabetes who were treated with the newer generation of insulin analog drugs did not have substantially better outcomes than those treated with less costly human insulin, according to a study by Yale School of Medicine researchers and colleagues at Kaiser Permanente.  The study is published in the June 23 issue of Journal...

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Diabetes: The insulin pill may finally be here

Individuals with type 1 diabetes must inject themselves with the required dose of insulin daily to manage their condition. In the future, injections may no longer be necessary; scientists are developing a viable way of delivering insulin in pill form. Researchers have developed a pill for the oral delivery of insulin, and they hope that...

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Alzheimer’s disease—why insulin is a new suspect

Johnson and Johnson recently announced that it was halting a clinical trial for a new Alzheimer’s drug after safety issues emerged. This latest failure adds to the dozens of large, costly clinical trials that have shown no effect in treating this devastating disease. The growing list of failures should give us pause for thought – have we...

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Oral insulin proving successful in human clinical trials

For decades researchers have worked to find a way to orally administer insulin effectively to patients with diabetes. Now, this game-changing treatment is one step closer to reality, with pharmaceutical company Oramed embarking on a final Phase 2b human clinical trial to prove the efficacy of its oral insulin before moving to the final stages of trials...

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Diabetes-associated pain linked to disrupted insulin signalling

The chronic pain experienced by a number of patients with diabetes has widely been assumed to originate from damage to blood vessels or to local tissue surrounding neurons caused by high blood-sugar levels. However, a new study reports that in fruit flies, this pain hypersensitivity results instead from disrupted insulin signaling in pain sensory neurons....

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Resistance exercise improves insulin resistance, glucose levels

A new study suggests that resistance exercise may improve indicators of type 2 diabetes by increasing expression of a protein that regulates blood sugar (glucose) absorption in the body. The paper, published ahead of print in the American Journal of Physiology-Endocrinology and Metabolism, was chosen as an APSselect article for April. People with type 2 diabetes...

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A new role for insulin as a vital factor in maintaining stem cells

New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in mammals New research conducted at the stem cell centre, DanStem, at the University of Copenhagen shows that insulin is a key determinant of embryonic stem cell potency in...