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Scientists identify new pathway activated by interferon-gamma that leads to tumor cell death
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Scientists identify new pathway activated by interferon-gamma that leads to tumor cell death

by Denise Heady, University of California, Los Angeles Drug screening identifies RAF and ERK as the mediators of IFNγ-induced growth inhibition. (A) Workflow for the drug screen. The orange dots on the Z-score plot indicate expected hits that rescue IFNγ-mediated growth inhibition but do not affect cell growth in the absence of IFNγ. (B) Z-score plot...