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Intranasal vaccination produces potent systemic immunity against HIV and SARS-CoV-2 in animal models
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Intranasal vaccination produces potent systemic immunity against HIV and SARS-CoV-2 in animal models

by Delthia Ricks, Medical Xpress Long-lived antigen-specific IgG and IgA plasma cells are established in mice following intranasal immunization with amph-protein, without induction of anti-PEG antibodies. BALB/c mice (n = 3 animals per group) were immunized i.n. with 5 µg amph-eOD mixed with 25 µg cdGMP adjuvant and boosted 6 weeks later with the same...