by Chris Talbott, University of Washington School of Medicine A mosaic expression of two ion channels in dopamine neurons of a mouse’s brain. Researchers have found a way to control dopamine release. Credit: Larry Zweifel Researchers have identified two ion channel switches that regulate the release of dopamine in the brain, a first step that might one day lead...
Tag: <span>ion channel</span>
Ion channel regulates molecule that contributes to COPD
JANUARY 14, 2022 by Ludwig Maximilian University of Munich Immunofluorescence image of lung tissue showing co-localization of TRPML3 (green) and macrophages (red). Credit: Barbara Spix Chronic obstructive pulmonary disease—COPD for short—is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year. A...
Cell Reports publishes data supporting the importance of ion channel, Kv7.2/7.3 as a target in ALS
LAVOIEHEALTHSCIENCE CAMBRIDGE, Mass.–(BUSINESS WIRE)–QurAlis Corporation, a biotech company developing breakthrough precision medicines for ALS and other genetically validated neurodegenerative diseases, today announced the publication of an article in Cell Reportstitled Human Amyotrophic Lateral Sclerosis Excitability Phenotype Screen: Target Discovery and Validation by QurAlis founders Kasper Roet, Ph.D., Clifford Woolf, M.D., Ph.D., and Kevin Eggan, Ph.D., who pioneered a high-content, live-cell imaging...