FUDAN UNIVERSITY IMAGE: THE DEBRIS OF MICROGLIA (PROFESSIONAL PHAGOCYTES) IS PRIMARILY ENGULFED BY ASTROCYTES (NONPROFESSIONAL PHAGOCYTES), WHICH IS FACILITATED BY C4 OPSONIZATION. THE PHAGOCYTOSED DEBRIS IS THEN DEGRADED IN ASTROCYTES VIA RUBICON-DEPENDENT LAP, AND MICROGLIAL DEBRIS-CONTAINING LAPOSOMES SUBSEQUENTLY FUSE WITH LYSOSOMES TO FORM PHAGOLYSOSOMES, IN WHICH THE DEBRIS IS DEGRADED. CREDIT: THE AUTHORS. Microglia are...
