by The Korea Advanced Institute of Science and Technology (KAIST) Genetic composition of rc-L1s is inherited from the parents. The methylation landscape of rc-L1 promoters is predominantly determined by global DNA demethylation, followed by remethylation processes in the developmental stages. Then, when an rc-L1 is promoter demethylated in a specific cell lineage, the source expresses L1...
by Bill Hathaway, Yale University Graphical abstract. Credit: Neuron (2022). DOI: 10.1016/j.neuron.2022.08.011 Massive, repetitive stretches of DNA in the human genome may harbor hints about the onset of a rare, inherited neurodegenerative disorder called ataxia-telangiectasia as well as other related diseases, a new Yale School of Medicine study finds. The findings also point to possible directions for...
DUKE UNIVERSITY DURHAM, N.C. — Biomedical engineers at Duke University believe they have discovered the physical mechanism that causes high doses of antibiotics to promote the spread of antibiotic resistance between bacteria. The culprit, they say, is an overabundance of “jumping genes,” called transposons, that carry the genetic instructions for resistance from the cell’s source...
