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Researchers identify key source of T cell ‘exhaustion’
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Researchers identify key source of T cell ‘exhaustion’

by Dana-Farber Cancer Institute Graphical Abstract. Credit: Molecular Cell (2023). DOI: 10.1016/j.molcel.2023.02.026 Custom-made to attack cancer cells, CAR T-cell therapies have opened a new era in the treatment of human cancers, particularly, in hematologic malignancies. All too often, however, they display a frustrating trait inherited from the body’s own immune system cells: a drastic loss of cancer-fighting...